Development of an analytical method for dibutyl phthalate determination using Surrogate analyte approach

نویسندگان

  • Mehrdad Faizi Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences,Tehran, Iran.
  • Nima Naderi Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences,Tehran, Iran.
  • Vahid Farzanehfar Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences,Tehran, Iran.
چکیده مقاله:

Dibutyl phthalate (DBP) is a phthalic acid ester and is widely used in polymeric products to make them more flexible. DBP is found in almost every plastic material and is believed to be persistent in the environment. Various analytical methods have been used to measure DBP in different matrices. Considering the ubiquitous nature of DBP, the most important challenge in DBP analyses is the contamination of even analytical grade organic solvents with this compound and lack of availability of a true blank matrix to construct the calibration line. Standard addition method or using artificial matrices reduce the precision and accuracy of the results. In this study a surrogate analyte approach that is based on using deuterium labeled analyte (DBP-d4) to construct the calibration line was applied to determine DBP in hexane samples.

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development of an analytical method for dibutyl phthalate determination using surrogate analyte approach

dibutyl phthalate (dbp) is a phthalic acid ester and is widely used in polymeric products to make them more flexible. dbp is found in almost every plastic material and is believed to be persistent in the environment. various analytical methods have been used to measure dbp in different matrices. considering the ubiquitous nature of dbp, the most important challenge in dbp analyses is the contam...

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Development of an Analytical Method for Dibutyl Phthalate Determination Using Surrogate Analyte Approach

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عنوان ژورنال

دوره 16  شماره 1

صفحات  140- 145

تاریخ انتشار 2017-03-01

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